Metabolomics of Male Infertility: A New Tool for Diagnostic Tests

Infertility is a major health issue worldwide. Males and females contribute equally to this problem. Diagnostic semen analysis fails to identify 50% of male infertility disorders. In this regard, metabolomics as a new field of omics has been suggested to have the potential of solving and diagnosis o...

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Autores principales: Mehrparavar, Bahareh, Minai-Tehrani, Arash, Arjmand, Babak, Gilany, Kambiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486563/
https://www.ncbi.nlm.nih.gov/pubmed/31058049
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author Mehrparavar, Bahareh
Minai-Tehrani, Arash
Arjmand, Babak
Gilany, Kambiz
author_facet Mehrparavar, Bahareh
Minai-Tehrani, Arash
Arjmand, Babak
Gilany, Kambiz
author_sort Mehrparavar, Bahareh
collection PubMed
description Infertility is a major health issue worldwide. Males and females contribute equally to this problem. Diagnostic semen analysis fails to identify 50% of male infertility disorders. In this regard, metabolomics as a new field of omics has been suggested to have the potential of solving and diagnosis of the male infertility problems. Metabo-lome has a history of around 20 years. However, there are only limited metabolomics studies carried out regarding male infertility. In this review, the current metabolomics researches that have been done in infertile men were reviewed. Based on our own results, using human seminal plasma for metabolomics studies is highly recommended to find potential biomarkers and developing diagnosis tests for detection of main deficiencies in infertile men.
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spelling pubmed-64865632019-05-03 Metabolomics of Male Infertility: A New Tool for Diagnostic Tests Mehrparavar, Bahareh Minai-Tehrani, Arash Arjmand, Babak Gilany, Kambiz J Reprod Infertil Review Article Infertility is a major health issue worldwide. Males and females contribute equally to this problem. Diagnostic semen analysis fails to identify 50% of male infertility disorders. In this regard, metabolomics as a new field of omics has been suggested to have the potential of solving and diagnosis of the male infertility problems. Metabo-lome has a history of around 20 years. However, there are only limited metabolomics studies carried out regarding male infertility. In this review, the current metabolomics researches that have been done in infertile men were reviewed. Based on our own results, using human seminal plasma for metabolomics studies is highly recommended to find potential biomarkers and developing diagnosis tests for detection of main deficiencies in infertile men. Avicenna Research Institute 2019 /pmc/articles/PMC6486563/ /pubmed/31058049 Text en Copyright© 2019, Avicenna Research Institute. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mehrparavar, Bahareh
Minai-Tehrani, Arash
Arjmand, Babak
Gilany, Kambiz
Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title_full Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title_fullStr Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title_full_unstemmed Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title_short Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
title_sort metabolomics of male infertility: a new tool for diagnostic tests
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486563/
https://www.ncbi.nlm.nih.gov/pubmed/31058049
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AT gilanykambiz metabolomicsofmaleinfertilityanewtoolfordiagnostictests

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