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Binless normalization of Hi-C data provides significant interaction and difference detection independent of resolution
Chromosome conformation capture techniques, such as Hi-C, are fundamental in characterizing genome organization. These methods have revealed several genomic features, such as chromatin loops, whose disruption can have dramatic effects in gene regulation. Unfortunately, their detection is difficult;...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486590/ https://www.ncbi.nlm.nih.gov/pubmed/31028255 http://dx.doi.org/10.1038/s41467-019-09907-2 |