Cargando…
Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide
The crucial role of androgen receptor (AR) in prostate cancer development is well documented, and its inhibition is a mainstay of prostate cancer treatment. Here, we analyze the perturbations to the AR cistrome caused by a minor groove binding molecule that is designed to target a sequence found in...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486638/ https://www.ncbi.nlm.nih.gov/pubmed/30838415 http://dx.doi.org/10.1093/nar/gkz153 |