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Using long-read sequencing to detect imprinted DNA methylation

Systematic variation in the methylation of cytosines at CpG sites plays a critical role in early development of humans and other mammals. Of particular interest are regions of differential methylation between parental alleles, as these often dictate monoallelic gene expression, resulting in parent o...

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Detalles Bibliográficos
Autores principales: Gigante, Scott, Gouil, Quentin, Lucattini, Alexis, Keniry, Andrew, Beck, Tamara, Tinning, Matthew, Gordon, Lavinia, Woodruff, Chris, Speed, Terence P, Blewitt, Marnie E, Ritchie, Matthew E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486641/
https://www.ncbi.nlm.nih.gov/pubmed/30793194
http://dx.doi.org/10.1093/nar/gkz107