A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation

The transcription elongation factor Spt6 and the H3K36 methyltransferase Set2 are both required for H3K36 methylation and transcriptional fidelity in Saccharomyces cerevisiae. However, the nature of the requirement for Spt6 has remained elusive. By selecting for suppressors of a transcriptional defe...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Rajaraman, Marr, Sharon K, Kingston, Robert E, Winston, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486648/
https://www.ncbi.nlm.nih.gov/pubmed/30793188
http://dx.doi.org/10.1093/nar/gkz119

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