A double-blind randomized comparative clinical trial to evaluate the safety and efficacy of dendritic cell vaccine loaded with WT1 peptides (TLP0-001) in combination with S-1 in patients with advanced pancreatic cancer refractory to standard chemotherapy

BACKGROUND: Pancreatic cancer is a refractory malignancy, and the development of a new effective treatment strategy is needed. We generated a dendritic cell vaccine by culturing monocytes obtained by apheresis of blood from each patient, inducing their differentiation into dendritic cells, and pulsi...

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Detalles Bibliográficos
Autores principales: Katsuda, Masahiro, Miyazawa, Motoki, Ojima, Toshiyasu, Katanuma, Akio, Hakamada, Kenichi, Sudo, Kentaro, Asahara, Shingo, Endo, Itaru, Ueno, Makoto, Hara, Kazuo, Yamada, Suguru, Fujii, Tsutomu, Satoi, Sohei, Ioka, Tatsuya, Ohira, Masaichi, Akahori, Takahiro, Kitano, Masayuki, Nagano, Hiroaki, Furukawa, Masayuki, Adachi, Tomohiko, Yamaue, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486956/
https://www.ncbi.nlm.nih.gov/pubmed/31029154
http://dx.doi.org/10.1186/s13063-019-3332-5

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