Cell and context-dependent sorting of neuropathy-associated protein NDRG1 – insights from canine tissues and primary Schwann cell cultures

BACKGROUND: Mutations in the N-myc downstream-regulated gene 1 (NDRG1) can cause degenerative polyneuropathy in humans, dogs, and rodents. In humans, this motor and sensory neuropathy is known as Charcot-Marie-Tooth disease type 4D, and it is assumed that analogous canine diseases can be used as mod...

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Detalles Bibliográficos
Autores principales: Skedsmo, Fredrik S., Tranulis, Michael A., Espenes, Arild, Prydz, Kristian, Matiasek, Kaspar, Gunnes, Gjermund, Hermansen, Lene C., Jäderlund, Karin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487035/
https://www.ncbi.nlm.nih.gov/pubmed/31029158
http://dx.doi.org/10.1186/s12917-019-1872-2

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