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An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth

Squamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC...

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Autores principales: Cheung, Johnson, Al Afif, Ayham, Bullock, Martin Joseph, Robertson, Chad, Hart, Robert, Goodday, Reginald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487125/
https://www.ncbi.nlm.nih.gov/pubmed/31110834
http://dx.doi.org/10.1155/2019/8360357
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author Cheung, Johnson
Al Afif, Ayham
Bullock, Martin Joseph
Robertson, Chad
Hart, Robert
Goodday, Reginald
author_facet Cheung, Johnson
Al Afif, Ayham
Bullock, Martin Joseph
Robertson, Chad
Hart, Robert
Goodday, Reginald
author_sort Cheung, Johnson
collection PubMed
description Squamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC may also mimic an infectious condition and therefore can pose a diagnostic challenge even for the most experienced clinicians. Herein, we report a case of mandibular squamous cell carcinoma in a 53-year-old male who presented with symptoms of right facial swelling, trismus, pain, and right-sided lip paresthesia. The patient underwent a surgical removal of the presumed infected third molar of the right mandible, but histopathological analysis of the associated soft tissue unexpectedly yielded squamous cell carcinoma. Given the biopsy-proven diagnosis, the patient received a mandibular resection of the tumor followed by primary reconstruction with a fibular free flap. Patients presenting with symptoms mimicking odontogenic infections should receive vigilant attention by clinicians with regard to the disease history, clinical signs, radiographic evidence, and decision for histopathological analysis. This is especially true in the context of impacted dentition, where malignancy must be considered when formulating a differential diagnosis.
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spelling pubmed-64871252019-05-20 An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth Cheung, Johnson Al Afif, Ayham Bullock, Martin Joseph Robertson, Chad Hart, Robert Goodday, Reginald Case Rep Surg Case Report Squamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC may also mimic an infectious condition and therefore can pose a diagnostic challenge even for the most experienced clinicians. Herein, we report a case of mandibular squamous cell carcinoma in a 53-year-old male who presented with symptoms of right facial swelling, trismus, pain, and right-sided lip paresthesia. The patient underwent a surgical removal of the presumed infected third molar of the right mandible, but histopathological analysis of the associated soft tissue unexpectedly yielded squamous cell carcinoma. Given the biopsy-proven diagnosis, the patient received a mandibular resection of the tumor followed by primary reconstruction with a fibular free flap. Patients presenting with symptoms mimicking odontogenic infections should receive vigilant attention by clinicians with regard to the disease history, clinical signs, radiographic evidence, and decision for histopathological analysis. This is especially true in the context of impacted dentition, where malignancy must be considered when formulating a differential diagnosis. Hindawi 2019-04-11 /pmc/articles/PMC6487125/ /pubmed/31110834 http://dx.doi.org/10.1155/2019/8360357 Text en Copyright © 2019 Johnson Cheung et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cheung, Johnson
Al Afif, Ayham
Bullock, Martin Joseph
Robertson, Chad
Hart, Robert
Goodday, Reginald
An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_full An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_fullStr An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_full_unstemmed An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_short An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_sort unusual case of mandibular squamous cell carcinoma in intimacy with an impacted wisdom tooth
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487125/
https://www.ncbi.nlm.nih.gov/pubmed/31110834
http://dx.doi.org/10.1155/2019/8360357
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