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Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells
Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively high. Hence, how berberine enters and reaches a cytocidal concentration remains to be elucidated. In the p...
Autores principales: | Li, Qiao, Zhou, Ting, Liu, Chang, Wang, Xiao-Yu, Zhang, Ji-Quan, Wu, Fei, Lin, Ge, Ma, Yue-Ming, Ma, Bing-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487271/ https://www.ncbi.nlm.nih.gov/pubmed/30944202 http://dx.doi.org/10.1042/BSR20190477 |
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