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Gene replacement therapy in a model of Charcot-Marie-Tooth 4C neuropathy

Charcot-Marie-Tooth disease type 4C is the most common recessively inherited demyelinating neuropathy that results from loss of function mutations in the SH3TC2 gene. Sh3tc2(−/−) mice represent a well characterized disease model developing early onset progressive peripheral neuropathy with hypo- and...

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Detalles Bibliográficos
Autores principales:	Schiza, Natasa, Georgiou, Elena, Kagiava, Alexia, Médard, Jean-Jacques, Richter, Jan, Tryfonos, Christina, Sargiannidou, Irene, Heslegrave, Amanda J, Rossor, Alexander M, Zetterberg, Henrik, Reilly, Mary M, Christodoulou, Christina, Chrast, Roman, Kleopa, Kleopas A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487329/ https://www.ncbi.nlm.nih.gov/pubmed/30907403 http://dx.doi.org/10.1093/brain/awz064

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