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Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions

BACKGROUND: Study shows that signal transducer and activator of transcription 3 (STAT3) can increase the Warburg effect by stimulating hexokinase 2 in breast cancer and upregulate lactate dehydrogenase A and pyruvate dehydrogenase kinase 1 in myeloma. STAT3 and pyruvate kinase M2 (PKM2) can also be...

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Detalles Bibliográficos
Autores principales:	Bi, Yang-Hui, Han, Wen-Qi, Li, Ruo-Fei, Wang, Yun-Jiao, Du, Zun-Shu, Wang, Xue-Jiang, Jiang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2019
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487376/ https://www.ncbi.nlm.nih.gov/pubmed/31086462 http://dx.doi.org/10.3748/wjg.v25.i16.1936

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