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Mapping the Azolog Space Enables the Optical Control of New Biological Targets
[Image: see text] Photopharmacology relies on molecules that change their biological activity upon irradiation. Many of these are derived from known drugs by replacing their core with an isosteric azobenzene photoswitch (azologization). The question is how many of the known bioactive ligands could b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487453/ https://www.ncbi.nlm.nih.gov/pubmed/31041380 http://dx.doi.org/10.1021/acscentsci.8b00881 |