Cardiac‐specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure

Growing evidence suggests that redox‐sensitive proteins including glutaredoxins (Grxs) can protect cardiac muscle cells from oxidative stress‐induced damage. Mammalian Grx3 has been shown to be critical in regulating cellular redox states. However, how Grx3 affects cardiac function by modulating rea...

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Detalles Bibliográficos
Autores principales: Donelson, Jimmonique, Wang, Qiongling, Monroe, Tanner O., Jiang, Xiqian, Zhou, Jianjie, Yu, Han, Mo, Qianxing, Sun, Qin, Marini, Juan C., Wang, Xinquan, Nakata, Paul A., Hirschi, Kendal D., Wang, Jin, Rodney, George G., Wehrens, Xander H.T., Cheng, Ninghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487472/
https://www.ncbi.nlm.nih.gov/pubmed/31033205
http://dx.doi.org/10.14814/phy2.14071

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