Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

ABSTRACT: Pediatric high grade gliomas (pHGG), including diffuse intrinsic pontine gliomas (DIPGs), are aggressive tumors with a dismal outcome. Radiotherapy (RT) is part of the standard of care of these tumors; however, radiotherapy only leads to a transient clinical improvement. Delta-24-RGD is a...

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Detalles Bibliográficos
Autores principales: Martinez-Velez, Naiara, Marigil, Miguel, García-Moure, Marc, Gonzalez-Huarriz, Marisol, Aristu, Jose Javier, Ramos-García, Luis-Isaac, Tejada, Sonia, Díez-Valle, Ricardo, Patiño-García, Ana, Becher, Oren J., Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487528/
https://www.ncbi.nlm.nih.gov/pubmed/31036068
http://dx.doi.org/10.1186/s40478-019-0714-6

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