Cargando…

Molecular Profiling of Hard-to-Treat Childhood and Adolescent Cancers

IMPORTANCE: Little progress in pediatric cancer treatment has been noted in the past decade, urging the development of novel therapeutic strategies for adolescents and children with hard-to-treat cancers. Use of comprehensive molecular profiling in the clinical management of children and adolescents...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khater, Fida, Vairy, Stephanie, Langlois, Sylvie, Dumoucel, Sophie, Sontag, Thomas, St-Onge, Pascal, Bittencourt, Henrique, Dal Soglio, Dorothée, Champagne, Josette, Duval, Michel, Leclerc, Jean-Marie, Laverdiere, Caroline, Tran, Thai Hoa, Patey, Natalie, Ellezam, Benjamin, Perreault, Sébastien, Piché, Nelson, Samson, Yvan, Teira, Pierre, Jabado, Nada, Michon, Bruno, Brossard, Josée, Marzouki, Monia, Cellot, Sonia, Sinnett, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487576/ https://www.ncbi.nlm.nih.gov/pubmed/31026031 http://dx.doi.org/10.1001/jamanetworkopen.2019.2906

Ejemplares similares

Recurrent somatic BRAF insertion (p.V504_R506dup): a tumor marker and a potential therapeutic target in pilocytic astrocytoma
por: Khater, Fida, et al.
Publicado: (2018)

Clinical response to dabrafenib and chemotherapy in clonally-related histiocytosis and acute lymphoblastic leukemia
por: Hubert, Gervaise, et al.
Publicado: (2022)

Improvement of the Outcome of Relapsed or Refractory Acute Lymphoblastic Leukemia in Children Using a Risk-Based Treatment Strategy
por: Ceppi, Francesco, et al.
Publicado: (2016)

Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001
por: Tran, Thai Hoa, et al.
Publicado: (2022)

Multimodal Treatment Including Intracavitary Chemotherapy for Recurrent Pediatric Pleuropulmonary Blastoma
por: Habti, Merieme, et al.
Publicado: (2021)

CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia
por: Vairy, Stephanie, et al.
Publicado: (2018)

Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children
por: Benadiba, Joy, et al.
Publicado: (2018)

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations
por: Spinella, Jean-François, et al.
Publicado: (2016)

IDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome
por: Mourad, Stéphanie, et al.
Publicado: (2019)

Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors
por: England, Jade, et al.
Publicado: (2017)

Upfront BRAF/MEK inhibitors for treatment of high-grade glioma: A case report and review of the literature
por: Arbour, Gabrielle, et al.
Publicado: (2022)

Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity
por: Caron, Maxime, et al.
Publicado: (2020)

Publisher Correction: Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity
por: Caron, Maxime, et al.
Publicado: (2021)

Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes
por: Caron, Maxime, et al.
Publicado: (2018)

Identification of genetic association between cardiorespiratory fitness and the trainability genes in childhood acute lymphoblastic leukemia survivors
por: Caru, Maxime, et al.
Publicado: (2019)

Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric Patients
por: Perreault, Sébastien, et al.
Publicado: (2021)

French-language adaptation of the 16D and 17D Quality of Life measures and score description in two Canadian pediatric samples
por: Rondeau, Émélie, et al.
Publicado: (2021)

Phenotype and outcomes of very early onset and early onset inflammatory bowel diseases in a Montreal pediatric cohort
por: Chapuy, Laurence, et al.
Publicado: (2023)

Germline Platelet-derived growth factor receptor beta p.R987W pathogenic variant in 2 children with brain tumors
por: Han, HyeRim, et al.
Publicado: (2023)

NFB-08. TRAM-01: A Phase 2 study of trametinib for pediatric patients with neurofibromatosis type 1 and plexiform neurofibromas
por: Kiaei, Dorsa Sadat, et al.
Publicado: (2022)

Nutrition education and cooking workshops for families of children with cancer: a feasibility study
por: Beaulieu-Gagnon, S., et al.
Publicado: (2019)

Identification of genetic variants associated with skeletal muscle function deficit in childhood acute lymphoblastic leukemia survivors
por: Nadeau, Geneviève, et al.
Publicado: (2019)

Infectious Events Prior to Chemotherapy Initiation in Children with Acute Myeloid Leukemia
por: Portwine, Carol, et al.
Publicado: (2013)

Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group
por: Cellot, Sonia, et al.
Publicado: (2013)

Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients
por: Abaji, Rachid, et al.
Publicado: (2017)

Improvement of Diet after an Early Nutritional Intervention in Pediatric Oncology
por: Napartuk, Mélanie, et al.
Publicado: (2023)

An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data
por: Sommerkamp, Alexander C., et al.
Publicado: (2020)

Case report: Success of allogeneic hematopoietic stem cell transplantation for refractory systemic-onset juvenile idiopathic arthritis
por: Beaufils, Camille, et al.
Publicado: (2023)

Diet Quality Is Associated with Cardiometabolic Outcomes in Survivors of Childhood Leukemia
por: Bérard, Sophie, et al.
Publicado: (2020)

Infections in children with down syndrome and acute myeloid leukemia: a report from the Canadian infections in AML research group
por: Tran, Thai Hoa, et al.
Publicado: (2013)

LncRNAs downregulated in childhood acute lymphoblastic leukemia modulate apoptosis, cell migration, and DNA damage response
por: Gioia, Romain, et al.
Publicado: (2017)

Development and relative validation of a food frequency questionnaire for French-Canadian adolescent and young adult survivors of acute lymphoblastic leukemia
por: Morel, Sophia, et al.
Publicado: (2018)

Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors
por: Fournier, Maryse, et al.
Publicado: (2019)

Dietary Intakes Are Associated with HDL-Cholesterol in Survivors of Childhood Acute Lymphoblastic Leukaemia
por: Morel, Sophia, et al.
Publicado: (2019)

Early Nutritional Intervention to Promote Healthy Eating Habits in Pediatric Oncology: A Feasibility Study
por: Bélanger, Véronique, et al.
Publicado: (2022)

Abnormal HDL lipid and protein composition following pediatric cancer treatment: an associative study
por: Bélanger, Véronique, et al.
Publicado: (2023)

Influence of genetic factors on long-term treatment related neurocognitive complications, and on anxiety and depression in survivors of childhood acute lymphoblastic leukemia: The Petale study
por: Petrykey, Kateryna, et al.
Publicado: (2019)

A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway: TRAM-01
por: Perreault, Sébastien, et al.
Publicado: (2019)

LGG-25. A PHASE 2 STUDY OF TRAMETINIB FOR PATIENTS WITH PEDIATRIC GLIOMA WITH ACTIVATION OF THE MAPK/ERK PATHWAY. TRAM-01
por: Perreault, Sébastien, et al.
Publicado: (2020)

2699. Pneumococcal Vaccination During Chemotherapy in Children Treated for Acute Lymphoblastic Leukemia
por: Dorval, Sarah, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cgaqmqio1hg5gb780bch3tbfqv