The long noncoding RNA HORAS5 mediates castration‐resistant prostate cancer survival by activating the androgen receptor transcriptional program

Prostate cancer (PCa) is driven by the androgen receptor (AR)‐signaling axis. Hormonal therapy often mitigates PCa progression, but a notable number of cases progress to castration‐resistant PCa (CRPC). CRPC retains AR activity and is incurable. Long noncoding RNA (lncRNA) represent an uncharted reg...

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Detalles Bibliográficos
Autores principales: Parolia, Abhijit, Venalainen, Erik, Xue, Hui, Mather, Rebecca, Lin, Dong, Wu, Rebecca, Pucci, Perla, Rogalski, Jason, Evans, Joseph R., Feng, Felix, Collins, Colin C., Wang, Yuzhuo, Crea, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487714/
https://www.ncbi.nlm.nih.gov/pubmed/30776192
http://dx.doi.org/10.1002/1878-0261.12471

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