Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe‐Dnmts axis

DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells while decreasing their doubling time. Here, we show that incubation of prostate...

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Detalles Bibliográficos
Autores principales: Strmiska, Vladislav, Michalek, Petr, Lackova, Zuzana, Guran, Roman, Krizkova, Sona, Vanickova, Lucie, Zitka, Ondrej, Stiborova, Marie, Eckschlager, Tomas, Klejdus, Borivoj, Pacik, Dalibor, Tvrdikova, Eliska, Keil, Claudia, Haase, Hajo, Adam, Vojtech, Heger, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487735/
https://www.ncbi.nlm.nih.gov/pubmed/30628163
http://dx.doi.org/10.1002/1878-0261.12439

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