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Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis

Multiple myeloma (MM) is a malignant neoplasm of plasma, and exhibits several harmful effects including osteolytic injuries, hypercalcemia, and immune dysfunction. Many patients with MM succumb to the underlying malignancy. An S-phase kinase-related protein 2 (Skp2) inhibitor, designated SKPin C1, h...

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Detalles Bibliográficos
Autores principales: Yang, Ying, Yan, Wei, Liu, Zhuogang, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487740/
https://www.ncbi.nlm.nih.gov/pubmed/31038581
http://dx.doi.org/10.1590/1414-431X20198412

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