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Understanding p53 functions through p53 antibodies
TP53 is the most frequently mutated gene across all cancer types. Our understanding of its functions has evolved since its discovery four decades ago. Initially thought to be an oncogene, it was later realized to be a critical tumour suppressor. A significant amount of our knowledge about p53 functi...
Autores principales: | Sabapathy, Kanaga, Lane, David P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487784/ https://www.ncbi.nlm.nih.gov/pubmed/30907951 http://dx.doi.org/10.1093/jmcb/mjz010 |
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