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Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience

BACKGROUND: Interventional radiology (IR) is an indispensable component of multidisciplinary care in various gastrointestinal (GI) diseases. The literature on safety and utility of IR is limited in children. OBJECTIVES: In this study, we aim to analyze the outcomes of IR in various pediatric GI dise...

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Autores principales: Nabi, Zaheer, Singh, Jagadeesh R, Haris, Arafat, Shava, Upender, Chavan, Radhika, Nageshwar Reddy, Duvvur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487811/
https://www.ncbi.nlm.nih.gov/pubmed/31061889
http://dx.doi.org/10.1002/jgh3.12119
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author Nabi, Zaheer
Singh, Jagadeesh R
Haris, Arafat
Shava, Upender
Chavan, Radhika
Nageshwar Reddy, Duvvur
author_facet Nabi, Zaheer
Singh, Jagadeesh R
Haris, Arafat
Shava, Upender
Chavan, Radhika
Nageshwar Reddy, Duvvur
author_sort Nabi, Zaheer
collection PubMed
description BACKGROUND: Interventional radiology (IR) is an indispensable component of multidisciplinary care in various gastrointestinal (GI) diseases. The literature on safety and utility of IR is limited in children. OBJECTIVES: In this study, we aim to analyze the outcomes of IR in various pediatric GI diseases. METHODS: The data of children (≤18 years) who underwent radiological interventions for GI disorders (2009–2017) were analyzed, retrospectively. The indications for interventions included vascular (Budd Chiari syndrome [BCS], pseudoaneurysm) and nonvascular (pancreatic fluid collections [PFCs], cholangitis and anastomotic biliary strictures). The outcomes of radiological interventions, including success and adverse events, were assessed. RESULTS: A total of 93 children (mean age 13.45 ± 4.09 years) underwent radiological interventions for vascular (chronic BCS = 14, pseudoaneurysm = 28) or nonvascular (PFCs = 33, hepaticojejunostomy strictures or leaks = 12, cholangitis = 6) indications. Of 33 children who underwent drainage of PFCs, clinical success was noticed in 32 children during a mean follow‐up of 32.4 ± 21.66 months; 11 children with persistent external pancreatic fistula were managed with endoscopic pancreatic ductal stenting (8 children) and internalization of transgastric drain (3 children). In children who underwent hepatic vein or inferior vena cava stenting for BCS, mean stent patency was 78.57% during a follow‐up of 24.1 ± 13.78 months. In children with pseudoaneurysms, angioembolization was successfully performed in 92.8% patients. Re‐bleeding was noticed in two children, one of whom required reintervention. In children who underwent percutaneous transhepatic biliary drainage, resolution of anastomotic strictures was noticed in all during a follow‐up of 36.1 ± 13.73 months. CONCLUSION: Interventional radiology is safe and effective in the management of various pediatric GI diseases.
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spelling pubmed-64878112019-05-06 Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience Nabi, Zaheer Singh, Jagadeesh R Haris, Arafat Shava, Upender Chavan, Radhika Nageshwar Reddy, Duvvur JGH Open Original Articles BACKGROUND: Interventional radiology (IR) is an indispensable component of multidisciplinary care in various gastrointestinal (GI) diseases. The literature on safety and utility of IR is limited in children. OBJECTIVES: In this study, we aim to analyze the outcomes of IR in various pediatric GI diseases. METHODS: The data of children (≤18 years) who underwent radiological interventions for GI disorders (2009–2017) were analyzed, retrospectively. The indications for interventions included vascular (Budd Chiari syndrome [BCS], pseudoaneurysm) and nonvascular (pancreatic fluid collections [PFCs], cholangitis and anastomotic biliary strictures). The outcomes of radiological interventions, including success and adverse events, were assessed. RESULTS: A total of 93 children (mean age 13.45 ± 4.09 years) underwent radiological interventions for vascular (chronic BCS = 14, pseudoaneurysm = 28) or nonvascular (PFCs = 33, hepaticojejunostomy strictures or leaks = 12, cholangitis = 6) indications. Of 33 children who underwent drainage of PFCs, clinical success was noticed in 32 children during a mean follow‐up of 32.4 ± 21.66 months; 11 children with persistent external pancreatic fistula were managed with endoscopic pancreatic ductal stenting (8 children) and internalization of transgastric drain (3 children). In children who underwent hepatic vein or inferior vena cava stenting for BCS, mean stent patency was 78.57% during a follow‐up of 24.1 ± 13.78 months. In children with pseudoaneurysms, angioembolization was successfully performed in 92.8% patients. Re‐bleeding was noticed in two children, one of whom required reintervention. In children who underwent percutaneous transhepatic biliary drainage, resolution of anastomotic strictures was noticed in all during a follow‐up of 36.1 ± 13.73 months. CONCLUSION: Interventional radiology is safe and effective in the management of various pediatric GI diseases. Wiley Publishing Asia Pty Ltd 2018-12-27 /pmc/articles/PMC6487811/ /pubmed/31061889 http://dx.doi.org/10.1002/jgh3.12119 Text en © 2018 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Nabi, Zaheer
Singh, Jagadeesh R
Haris, Arafat
Shava, Upender
Chavan, Radhika
Nageshwar Reddy, Duvvur
Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title_full Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title_fullStr Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title_full_unstemmed Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title_short Outcome of radiological interventions in pediatric gastrointestinal diseases: A large tertiary center experience
title_sort outcome of radiological interventions in pediatric gastrointestinal diseases: a large tertiary center experience
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487811/
https://www.ncbi.nlm.nih.gov/pubmed/31061889
http://dx.doi.org/10.1002/jgh3.12119
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