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Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome
OBJECTIVE: To evaluate the clinical profile and outcome of arterial pseudoaneurysms (PSA) associated with acute and chronic pancreatitis (CP). METHODS: Records of all patients of pancreatitis from 2010 to 2016 were analyzed retrospectively for the development PSAs; clinical profile and outcome param...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487818/ https://www.ncbi.nlm.nih.gov/pubmed/31061887 http://dx.doi.org/10.1002/jgh3.12116 |
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author | Mallick, Bipadabhanjan Malik, Sarthak Gupta, Pankaj Gorsi, Ujjwal Kochhar, Suman Gupta, Vikas Yadav, Thakur Deen Dhaka, Narendra Sinha, Saroj K Kochhar, Rakesh |
author_facet | Mallick, Bipadabhanjan Malik, Sarthak Gupta, Pankaj Gorsi, Ujjwal Kochhar, Suman Gupta, Vikas Yadav, Thakur Deen Dhaka, Narendra Sinha, Saroj K Kochhar, Rakesh |
author_sort | Mallick, Bipadabhanjan |
collection | PubMed |
description | OBJECTIVE: To evaluate the clinical profile and outcome of arterial pseudoaneurysms (PSA) associated with acute and chronic pancreatitis (CP). METHODS: Records of all patients of pancreatitis from 2010 to 2016 were analyzed retrospectively for the development PSAs; clinical profile and outcome parameters were compared between PSAs associated with acute and CP. RESULTS: Of the 980 patients, 46 (all males, age 39.70 ± 11.78 years) developed PSAs, including 19 of 600 of acute pancreatitis (AP) and 27 of 380 of CP. The most common clinical presentation was bleeding (37, 80.4%). The majority of patients was managed nonsurgically, with endovascular embolization in 31 (67.4%) and percutaneous thrombin injection in 9 (19.6%) patients. Pseudoaneurysms in patients with AP were associated more often with fluid collections (94.7% vs. 55.6%, P = 0.004) with more requirement of surgery compared to patients with CP (15.8% vs. 3.7%, P = 0.033). The pattern of arteries involved with PSAs and outcome was similar in AP and CP patients. CONCLUSION: Arterial PSAs were more commonly associated with CP compared to AP with similar presentations. Associated fluid collections and requirement of surgical intervention were higher in PSAs in patients with AP compared to patients with CP. |
format | Online Article Text |
id | pubmed-6487818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-64878182019-05-06 Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome Mallick, Bipadabhanjan Malik, Sarthak Gupta, Pankaj Gorsi, Ujjwal Kochhar, Suman Gupta, Vikas Yadav, Thakur Deen Dhaka, Narendra Sinha, Saroj K Kochhar, Rakesh JGH Open Original Articles OBJECTIVE: To evaluate the clinical profile and outcome of arterial pseudoaneurysms (PSA) associated with acute and chronic pancreatitis (CP). METHODS: Records of all patients of pancreatitis from 2010 to 2016 were analyzed retrospectively for the development PSAs; clinical profile and outcome parameters were compared between PSAs associated with acute and CP. RESULTS: Of the 980 patients, 46 (all males, age 39.70 ± 11.78 years) developed PSAs, including 19 of 600 of acute pancreatitis (AP) and 27 of 380 of CP. The most common clinical presentation was bleeding (37, 80.4%). The majority of patients was managed nonsurgically, with endovascular embolization in 31 (67.4%) and percutaneous thrombin injection in 9 (19.6%) patients. Pseudoaneurysms in patients with AP were associated more often with fluid collections (94.7% vs. 55.6%, P = 0.004) with more requirement of surgery compared to patients with CP (15.8% vs. 3.7%, P = 0.033). The pattern of arteries involved with PSAs and outcome was similar in AP and CP patients. CONCLUSION: Arterial PSAs were more commonly associated with CP compared to AP with similar presentations. Associated fluid collections and requirement of surgical intervention were higher in PSAs in patients with AP compared to patients with CP. Wiley Publishing Asia Pty Ltd 2018-12-26 /pmc/articles/PMC6487818/ /pubmed/31061887 http://dx.doi.org/10.1002/jgh3.12116 Text en © 2018 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Mallick, Bipadabhanjan Malik, Sarthak Gupta, Pankaj Gorsi, Ujjwal Kochhar, Suman Gupta, Vikas Yadav, Thakur Deen Dhaka, Narendra Sinha, Saroj K Kochhar, Rakesh Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title | Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title_full | Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title_fullStr | Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title_full_unstemmed | Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title_short | Arterial pseudoaneurysms in acute and chronic pancreatitis: Clinical profile and outcome |
title_sort | arterial pseudoaneurysms in acute and chronic pancreatitis: clinical profile and outcome |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487818/ https://www.ncbi.nlm.nih.gov/pubmed/31061887 http://dx.doi.org/10.1002/jgh3.12116 |
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