Targeted lipid nanoparticle delivery of calcitriol to human monocyte-derived macrophages in vitro and in vivo: investigation of the anti-inflammatory effects of calcitriol

BACKGROUND: Vitamin D(3) possesses anti-inflammatory and modulatory properties in addition to its role in calcium and phosphate homeostasis. Upon activation, macrophages (M) can initiate and sustain pro-inflammatory cytokine production in inflammatory disorders and play a pathogenic role in certain...

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Detalles Bibliográficos
Autores principales: Rafique, Aisha, Etzerodt, Anders, Graversen, Jonas H, Moestrup, Søren K, Dagnæs-Hansen, Frederik, Møller, Holger Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488164/
https://www.ncbi.nlm.nih.gov/pubmed/31114197
http://dx.doi.org/10.2147/IJN.S192113

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