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Global brain ischemia in rats is associated with mitochondrial release and downregulation of Mfn2 in the cerebral cortex, but not the hippocampus
Mitochondria are crucial for neuronal cell survival and death through their functions in ATP production and the intrinsic pathway of apoptosis. Mitochondrial dysfunction is considered to play a central role in several serious human diseases, including neurodegenerative diseases, such as Parkinson...
Autores principales: | Klacanova, Katarina, Kovalska, Maria, Chomova, Maria, Pilchova, Ivana, Tatarkova, Zuzana, Kaplan, Peter, Racay, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488171/ https://www.ncbi.nlm.nih.gov/pubmed/31017259 http://dx.doi.org/10.3892/ijmm.2019.4168 |
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