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Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient

BACKGROUND AND PURPOSE: Fusarium species is an opportunistic mold that causes disseminated infections in immunocompromised patients. Given the high mortality rate of this infection, it is important to make a definite diagnosis when encountering suspected cases. CASE REPORT: Herein, we presented a 35...

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Autores principales: Mardani, Masoud, Khodashahi, Rozita, Lotfali, Ensieh, Abolghasemi, Sara, Hakemi-vala, Mojhde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Medical Mycology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488287/
https://www.ncbi.nlm.nih.gov/pubmed/31049455
http://dx.doi.org/10.18502/cmm.5.1.534
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author Mardani, Masoud
Khodashahi, Rozita
Lotfali, Ensieh
Abolghasemi, Sara
Hakemi-vala, Mojhde
author_facet Mardani, Masoud
Khodashahi, Rozita
Lotfali, Ensieh
Abolghasemi, Sara
Hakemi-vala, Mojhde
author_sort Mardani, Masoud
collection PubMed
description BACKGROUND AND PURPOSE: Fusarium species is an opportunistic mold that causes disseminated infections in immunocompromised patients. Given the high mortality rate of this infection, it is important to make a definite diagnosis when encountering suspected cases. CASE REPORT: Herein, we presented a 35-year-old man diagnosed with acute myeloid leukemia with a prolonged febrile neutropenic period and ecthyma gangrenosum-like lesions, along with fungemia and disseminated fusariosis. The patient died despite receiving combination therapy, perhaps due to the nonrecovery of neutrophil. CONCLUSION: Ecthyma gangrenosum-like lesions due to disseminated fusariosis might be easily misdiagnosed. Consequently, more attention should be paid to the cutaneous lesions in immunocompromised patients.
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spelling pubmed-64882872019-05-02 Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient Mardani, Masoud Khodashahi, Rozita Lotfali, Ensieh Abolghasemi, Sara Hakemi-vala, Mojhde Curr Med Mycol Case Report BACKGROUND AND PURPOSE: Fusarium species is an opportunistic mold that causes disseminated infections in immunocompromised patients. Given the high mortality rate of this infection, it is important to make a definite diagnosis when encountering suspected cases. CASE REPORT: Herein, we presented a 35-year-old man diagnosed with acute myeloid leukemia with a prolonged febrile neutropenic period and ecthyma gangrenosum-like lesions, along with fungemia and disseminated fusariosis. The patient died despite receiving combination therapy, perhaps due to the nonrecovery of neutrophil. CONCLUSION: Ecthyma gangrenosum-like lesions due to disseminated fusariosis might be easily misdiagnosed. Consequently, more attention should be paid to the cutaneous lesions in immunocompromised patients. Iranian Society of Medical Mycology 2019-03 /pmc/articles/PMC6488287/ /pubmed/31049455 http://dx.doi.org/10.18502/cmm.5.1.534 Text en Copyright© 2019, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mardani, Masoud
Khodashahi, Rozita
Lotfali, Ensieh
Abolghasemi, Sara
Hakemi-vala, Mojhde
Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title_full Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title_fullStr Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title_full_unstemmed Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title_short Disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
title_sort disseminated fusariosis with ecthyma gangrenosum-like lesions in a refractory acute myeloid leukemia patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488287/
https://www.ncbi.nlm.nih.gov/pubmed/31049455
http://dx.doi.org/10.18502/cmm.5.1.534
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