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Eomes transcription factor is required for the development and differentiation of invariant NKT cells

Eomes regulates the differentiation of CD8(+) T cells into effector and memory phases. However, its role in invariant (i)NKT cells remains unknown. Here, we show the impact of Eomes on iNKT cells in the thymus and peripheral tissue using conditional knockout (Eomes-cKO) mice. In the thymus, CD1d-tet...

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Detalles Bibliográficos
Autores principales:	Shimizu, Kanako, Sato, Yusuke, Kawamura, Masami, Nakazato, Hiroshi, Watanabe, Takashi, Ohara, Osamu, Fujii, Shin-ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488575/ https://www.ncbi.nlm.nih.gov/pubmed/31044175 http://dx.doi.org/10.1038/s42003-019-0389-3

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