LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

Long noncoding RNAs (lncRNAs) are emerging as regulators of fundamental biological processes. Here we report on the characterization of an intergenic lncRNA expressed in epithelial tissues which we termed EPR (Epithelial cell Program Regulator). EPR is rapidly downregulated by TGF-β and its sustaine...

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Detalles Bibliográficos
Autores principales: Rossi, Martina, Bucci, Gabriele, Rizzotto, Dario, Bordo, Domenico, Marzi, Matteo J., Puppo, Margherita, Flinois, Arielle, Spadaro, Domenica, Citi, Sandra, Emionite, Laura, Cilli, Michele, Nicassio, Francesco, Inga, Alberto, Briata, Paola, Gherzi, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488594/
https://www.ncbi.nlm.nih.gov/pubmed/31036808
http://dx.doi.org/10.1038/s41467-019-09754-1

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