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Characterization of the physical properties of tumor-derived spheroids reveals critical insights for pre-clinical studies
Three-dimensional spheroids are widely used as cancer models to study tumor cell proliferation and to evaluate new anticancer drugs. Growth-induced stress (i.e., stress that persists in tumors after external loads removal) influences tumor growth and resistance to treatment. However, it is not clear...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488646/ https://www.ncbi.nlm.nih.gov/pubmed/31036886 http://dx.doi.org/10.1038/s41598-019-43090-0 |