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Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties

Promoting general health in terms of obesity and diabetes prevention is recommended by health care systems. The objectives of this study were to isolate an efficient glucose-converting Komagataeibacter xylinus to cellulose and to evaluate the safety of the selected strain as a new generation of prob...

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Autores principales: Lavasani, Paria Sadat, Motevaseli, Elahe, Sanikhani, Nafiseh Sadat, Modarressi, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488717/
https://www.ncbi.nlm.nih.gov/pubmed/31183432
http://dx.doi.org/10.1016/j.heliyon.2019.e01571
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author Lavasani, Paria Sadat
Motevaseli, Elahe
Sanikhani, Nafiseh Sadat
Modarressi, Mohammad Hossein
author_facet Lavasani, Paria Sadat
Motevaseli, Elahe
Sanikhani, Nafiseh Sadat
Modarressi, Mohammad Hossein
author_sort Lavasani, Paria Sadat
collection PubMed
description Promoting general health in terms of obesity and diabetes prevention is recommended by health care systems. The objectives of this study were to isolate an efficient glucose-converting Komagataeibacter xylinus to cellulose and to evaluate the safety of the selected strain as a new generation of probiotics in the fight against obesity. Of the 97 samples, 43 K xylinus strains were isolated and evaluated for their glucose conversion rate and 5 strains were examined for probiotic activities by in vitro assays. A strain with significant performance was fed to rats in order to determine its safety status in vivo. The results revealed that the strain K.X.1 had high level of glucose conversion rate and significant survival rate in acidic pH and bile salt. No adverse clinical signs and bacterial translocation to rats’ organs were observed. The results showed that the strain of K. xylinus K.X.1 has suitable probiotic properties.
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spelling pubmed-64887172019-06-10 Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties Lavasani, Paria Sadat Motevaseli, Elahe Sanikhani, Nafiseh Sadat Modarressi, Mohammad Hossein Heliyon Article Promoting general health in terms of obesity and diabetes prevention is recommended by health care systems. The objectives of this study were to isolate an efficient glucose-converting Komagataeibacter xylinus to cellulose and to evaluate the safety of the selected strain as a new generation of probiotics in the fight against obesity. Of the 97 samples, 43 K xylinus strains were isolated and evaluated for their glucose conversion rate and 5 strains were examined for probiotic activities by in vitro assays. A strain with significant performance was fed to rats in order to determine its safety status in vivo. The results revealed that the strain K.X.1 had high level of glucose conversion rate and significant survival rate in acidic pH and bile salt. No adverse clinical signs and bacterial translocation to rats’ organs were observed. The results showed that the strain of K. xylinus K.X.1 has suitable probiotic properties. Elsevier 2019-04-28 /pmc/articles/PMC6488717/ /pubmed/31183432 http://dx.doi.org/10.1016/j.heliyon.2019.e01571 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Lavasani, Paria Sadat
Motevaseli, Elahe
Sanikhani, Nafiseh Sadat
Modarressi, Mohammad Hossein
Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title_full Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title_fullStr Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title_full_unstemmed Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title_short Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
title_sort komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488717/
https://www.ncbi.nlm.nih.gov/pubmed/31183432
http://dx.doi.org/10.1016/j.heliyon.2019.e01571
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