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Elamipretide Improves Mitochondrial Function in the Failing Human Heart

Negative alterations of mitochondria are known to occur in heart failure (HF). This study investigated the novel mitochondrial-targeted therapeutic agent elamipretide on mitochondrial and supercomplex function in failing human hearts ex vivo. Freshly explanted failing and nonfailing ventricular tiss...

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Detalles Bibliográficos
Autores principales:	Chatfield, Kathryn C., Sparagna, Genevieve C., Chau, Sarah, Phillips, Elisabeth K., Ambardekar, Amrut V., Aftab, Muhammad, Mitchell, Max B., Sucharov, Carmen C., Miyamoto, Shelley D., Stauffer, Brian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	CLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488757/ https://www.ncbi.nlm.nih.gov/pubmed/31061916 http://dx.doi.org/10.1016/j.jacbts.2018.12.005

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