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Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors

Age-related macular degeneration (AMD) is the leading cause of vision loss in the western world. Recent evidence suggests that RPE and photoreceptors have an interconnected metabolism and that mitochondrial damage in RPE is a trigger for degeneration in both RPE and photoreceptors in AMD. To test th...

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Detalles Bibliográficos
Autores principales:	Brown, Emily E., DeWeerd, Alexander J., Ildefonso, Cristhian J., Lewin, Alfred S., Ash, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488819/ https://www.ncbi.nlm.nih.gov/pubmed/31039480 http://dx.doi.org/10.1016/j.redox.2019.101201

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