Protective effects of novel derivatives of vitamin D(3) and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms

We tested whether novel CYP11A1-derived vitamin D(3)- and lumisterol-hydroxyderivatives, including 1,25(OH)(2)D(3), 20(OH)D(3), 1,20(OH)(2)D(3), 20,23(OH)(2)D(3), 1,20,23(OH)(3)D(3), lumisterol, 20(OH)L(3), 22(OH)L(3), 20,22(OH)(2)L(3), and 24(OH)L(3), can protect against UVB-induced damage in human...

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Detalles Bibliográficos
Autores principales: Chaiprasongsuk, Anyamanee, Janjetovic, Zorica, Kim, Tae-Kang, Jarrett, Stuart G., D'Orazio, John A., Holick, Michael F., Tang, Edith K.Y., Tuckey, Robert C., Panich, Uraiwan, Li, Wei, Slominski, Andrzej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488822/
https://www.ncbi.nlm.nih.gov/pubmed/31039479
http://dx.doi.org/10.1016/j.redox.2019.101206

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