An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid

We report the case of a 73-year-old woman with leukoderma induced by cosmetics containing ascorbic acid. She had noticed the sudden appearance of a hypopigmented macule on the cheek within 1 month after use of the cosmetics with the brand name Obaji C Serum. No history of use of rhododenol-containin...

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Detalles Bibliográficos
Autores principales: Takafuji, Madoka, Tanemura, Atsushi, Katayama, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489026/
https://www.ncbi.nlm.nih.gov/pubmed/31097935
http://dx.doi.org/10.1159/000499031
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author Takafuji, Madoka
Tanemura, Atsushi
Katayama, Ichiro
author_facet Takafuji, Madoka
Tanemura, Atsushi
Katayama, Ichiro
author_sort Takafuji, Madoka
collection PubMed
description We report the case of a 73-year-old woman with leukoderma induced by cosmetics containing ascorbic acid. She had noticed the sudden appearance of a hypopigmented macule on the cheek within 1 month after use of the cosmetics with the brand name Obaji C Serum. No history of use of rhododenol-containing cosmetics was declared. Histopathological analysis revealed that the number of matured melanocytes was apparently decreased, and T lymphocytes abundantly infiltrated mainly the perifollicular region. In addition to the discontinuation of using Obaji C Serum, phototherapy by excimer light was noticeably effective for repigmentation. To our knowledge, there has been no other report so far showing hypopigmented lesions induced by this cosmetic.
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spelling pubmed-64890262019-05-16 An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid Takafuji, Madoka Tanemura, Atsushi Katayama, Ichiro Case Rep Dermatol Single Case We report the case of a 73-year-old woman with leukoderma induced by cosmetics containing ascorbic acid. She had noticed the sudden appearance of a hypopigmented macule on the cheek within 1 month after use of the cosmetics with the brand name Obaji C Serum. No history of use of rhododenol-containing cosmetics was declared. Histopathological analysis revealed that the number of matured melanocytes was apparently decreased, and T lymphocytes abundantly infiltrated mainly the perifollicular region. In addition to the discontinuation of using Obaji C Serum, phototherapy by excimer light was noticeably effective for repigmentation. To our knowledge, there has been no other report so far showing hypopigmented lesions induced by this cosmetic. S. Karger AG 2019-03-28 /pmc/articles/PMC6489026/ /pubmed/31097935 http://dx.doi.org/10.1159/000499031 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Takafuji, Madoka
Tanemura, Atsushi
Katayama, Ichiro
An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title_full An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title_fullStr An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title_full_unstemmed An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title_short An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
title_sort extremely rare case of leukoderma induced by cosmetics containing ascorbic acid
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489026/
https://www.ncbi.nlm.nih.gov/pubmed/31097935
http://dx.doi.org/10.1159/000499031
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