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Establishment and characterization of a novel childhood acute lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and 17p deletions

BACKGROUND: Although contemporary chemotherapy has improved the cure rate of childhood acute lymphoblastic leukemia (ALL) to nearly 90%, relapsed/refractory ALL is still a leading cause of tumor-related death in children. To clarify the underlying mechanisms of relapsed/refractory childhood ALL, res...

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Detalles Bibliográficos
Autores principales: Zhu, Yiping, Yang, Rong, Gao, Ju, Zhang, Yanle, Zhang, Ge, Gu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489226/
https://www.ncbi.nlm.nih.gov/pubmed/31168295
http://dx.doi.org/10.1186/s12935-019-0834-x