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Effect of transcription inhibition and generation of suppressive viral non-coding RNAs

BACKGROUND: HIV-1 patients receiving combination antiretroviral therapy (cART) survive infection but require life-long adherence at high expense. In chronic cART-treated patients with undetectable viral titers, cell-associated viral RNA is still detectable, pointing to low-level viral transcriptiona...

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Detalles Bibliográficos
Autores principales: Pinto, Daniel O., Scott, Tristan A., DeMarino, Catherine, Pleet, Michelle L., Vo, Thy T., Saifuddin, Mohammed, Kovalskyy, Dmytro, Erickson, James, Cowen, Maria, Barclay, Robert A., Zeng, Chen, Weinberg, Marc S., Kashanchi, Fatah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489247/
https://www.ncbi.nlm.nih.gov/pubmed/31036006
http://dx.doi.org/10.1186/s12977-019-0475-0