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A high-fat diet induces rapid changes in the mouse hypothalamic proteome

BACKGROUND: Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain region, the hypothalamus. METHODS: Mice were fed either a low-fat diet (LFD) or H...

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Detalles Bibliográficos
Autores principales: McLean, Fiona H., Campbell, Fiona M., Langston, Rosamund F., Sergi, Domenico, Resch, Cibell, Grant, Christine, Morris, Amanda C., Mayer, Claus D., Williams, Lynda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489262/
https://www.ncbi.nlm.nih.gov/pubmed/31168311
http://dx.doi.org/10.1186/s12986-019-0352-9