STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models

Pancreatic cancer is characterized by an immune suppressive stromal reaction that creates a barrier to therapy. A murine transgenic pancreatic cancer cell line that recapitulates human disease was used to test whether a STimulator of Interferon Genes (STING) agonist could reignite immunologically in...

Descripción completa

Detalles Bibliográficos
Autores principales: Jing, Weiqing, McAllister, Donna, Vonderhaar, Emily P., Palen, Katie, Riese, Matthew J., Gershan, Jill, Johnson, Bryon D., Dwinell, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489306/
https://www.ncbi.nlm.nih.gov/pubmed/31036082
http://dx.doi.org/10.1186/s40425-019-0573-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489306/
https://www.ncbi.nlm.nih.gov/pubmed/31036082
http://dx.doi.org/10.1186/s40425-019-0573-5

Ejemplares similares