miR-140-5p could suppress tumor proliferation and progression by targeting TGFBRI/SMAD2/3 and IGF-1R/AKT signaling pathways in Wilms’ tumor

BACKGROUND: Wilms’ tumor is also called nephroblastoma and is the most common pediatric renal cancer. Several genetic and epigenetic factors have been found to account for the development of Wilms’ tumor. MiRNAs play important roles in this tumorigenic process. In the present study, we aimed to inve...

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Detalles Bibliográficos
Autores principales: Liu, Zhuo, He, Feng, OuYang, Shengrong, Li, Yuanyuan, Ma, Feifei, Chang, Huibo, Cao, Dingding, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489324/
https://www.ncbi.nlm.nih.gov/pubmed/31035970
http://dx.doi.org/10.1186/s12885-019-5609-1

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