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Development of a high resolution melting analysis assay for rapid identification of JAK2 V617F missense mutation and its validation
BACKGROUND: Myeloproliferative neoplasms (MPN) are heterogeneous diseases that classified by the presence of Philadelphia chromosome into Philadelphia chromosome negative (Ph-neg) and positive (Ph-pos) myeloproliferative neoplasms. In ph-neg group A somatic point mutation (c.1849G>T) in the JAK2...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489328/ https://www.ncbi.nlm.nih.gov/pubmed/31165012 http://dx.doi.org/10.1186/s40164-019-0134-0 |