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Development of a high resolution melting analysis assay for rapid identification of JAK2 V617F missense mutation and its validation

BACKGROUND: Myeloproliferative neoplasms (MPN) are heterogeneous diseases that classified by the presence of Philadelphia chromosome into Philadelphia chromosome negative (Ph-neg) and positive (Ph-pos) myeloproliferative neoplasms. In ph-neg group A somatic point mutation (c.1849G>T) in the JAK2...

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Detalles Bibliográficos
Autores principales: Moradabadi, Alireza, Farsinejad, Alireza, Khansarinejad, Behzad, Fatemi, Ahamd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489328/
https://www.ncbi.nlm.nih.gov/pubmed/31165012
http://dx.doi.org/10.1186/s40164-019-0134-0