Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

BACKGROUND: Genome-wide association studies (GWAS) of diseases and traits have found associations to gene regions but not the functional SNP or the gene mediating the effect. Difference in gene regulatory signals can be detected using chromatin immunoprecipitation and next-gen sequencing (ChIP-seq)...

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Detalles Bibliográficos
Autores principales: Cavalli, Marco, Baltzer, Nicholas, Pan, Gang, Bárcenas Walls, José Ramón, Smolinska Garbulowska, Karolina, Kumar, Chanchal, Skrtic, Stanko, Komorowski, Jan, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489362/
https://www.ncbi.nlm.nih.gov/pubmed/31036066
http://dx.doi.org/10.1186/s40246-019-0204-8

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