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Functionalized docetaxel-loaded lipid-based-nanosuspensions to enhance antitumor efficacy in vivo
Purpose: To further enhance the antitumor efficacy through targeted delivery, DTX loaded lipid-based-nanosuspensions (DTX-LNS) were prepared and functionalized by PEGylation or NGR modification to develop DSPE-PEG(2000) modified DTX-LNS (P-DTX-LNS) or DSPE-PEG(2000)-NGR modified DTX-LNS (N-DTX-LNS),...
Autores principales: | Pang, Xiuping, Wang, Tianqi, Jiang, Dandan, Mu, Weiwei, Zhang, Bo, Zhang, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489590/ https://www.ncbi.nlm.nih.gov/pubmed/31114190 http://dx.doi.org/10.2147/IJN.S191341 |
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