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M2 macrophages confer resistance to 5-fluorouracil in colorectal cancer through the activation of CCL22/PI3K/AKT signaling

Background: M2 macrophages are crucial components of tumor microenvironment that frequently associated with the resistance of therapeutic treatments in human cancers, but their role in the chemosensitivity of colorectal cancer (CRC) to 5-fluorouracil (5-FU) is still obscure. Methods: In our study, w...

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Detalles Bibliográficos
Autores principales:	Wei, Chen, Yang, Chaogang, Wang, Shuyi, Shi, Dongdong, Zhang, Chunxiao, Lin, Xiaobin, Xiong, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489624/ https://www.ncbi.nlm.nih.gov/pubmed/31114248 http://dx.doi.org/10.2147/OTT.S198126

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