Cargando…
The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety
Ossamycin from Streptomyces hygroscopicus var. ossamyceticus is an antifungal and cytotoxic polyketide and a potent inhibitor of the mitochondrial ATPase. Analysis of a near-complete genome sequence of the ossamycin producer has allowed the identification of the 127-kbp ossamycin biosynthetic gene c...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490886/ https://www.ncbi.nlm.nih.gov/pubmed/31039188 http://dx.doi.org/10.1371/journal.pone.0215958 |