Ribosomal RNA gene repeats associate with the nuclear pore complex for maintenance after DNA damage

The ribosomal RNA genes (rDNA) comprise a highly repetitive gene cluster. The copy number of genes at this locus can readily change and is therefore one of the most unstable regions of the genome. DNA damage in rDNA occurs after binding of the replication fork blocking protein Fob1 in S phase, which...

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Detalles Bibliográficos
Autores principales: Horigome, Chihiro, Unozawa, Eri, Ooki, Takamasa, Kobayashi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490929/
https://www.ncbi.nlm.nih.gov/pubmed/30998688
http://dx.doi.org/10.1371/journal.pgen.1008103

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