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Distinct phenotype and function of circulating Vδ1(+) and Vδ2(+) γδT-cells in acute and chronic hepatitis B
Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status, we examined the frequency, phenotype and function of peripheral blood Vδ1(+) and Vδ2(+)...
Autores principales: | Chang, Kyong-Mi, Traum, Daniel, Park, Jang-June, Ho, Suzanne, Ojiro, Keisuke, Wong, David K., Wahed, Abdus S., Terrault, Norah A., Khalili, Mandana, Sterling, Richard K., Janssen, Harry L. A., Shuhart, Margaret C., Lau, Daryl T., Roberts, Lewis R., Johnson, Geoffrey S., Kaplan, David E., Betts, Michael R., Lee, William M., Lok, Anna S. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490945/ https://www.ncbi.nlm.nih.gov/pubmed/30998783 http://dx.doi.org/10.1371/journal.ppat.1007715 |
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