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Distinct phenotype and function of circulating Vδ1(+) and Vδ2(+) γδT-cells in acute and chronic hepatitis B

Hepatitis B virus (HBV) persists with global and virus-specific T-cell dysfunction, without T-cell based correlates of outcomes. To determine if γδT-cells are altered in HBV infection relative to clinical status, we examined the frequency, phenotype and function of peripheral blood Vδ1(+) and Vδ2(+)...

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Detalles Bibliográficos
Autores principales: Chang, Kyong-Mi, Traum, Daniel, Park, Jang-June, Ho, Suzanne, Ojiro, Keisuke, Wong, David K., Wahed, Abdus S., Terrault, Norah A., Khalili, Mandana, Sterling, Richard K., Janssen, Harry L. A., Shuhart, Margaret C., Lau, Daryl T., Roberts, Lewis R., Johnson, Geoffrey S., Kaplan, David E., Betts, Michael R., Lee, William M., Lok, Anna S. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490945/
https://www.ncbi.nlm.nih.gov/pubmed/30998783
http://dx.doi.org/10.1371/journal.ppat.1007715

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