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The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression
Cannabinoid type one receptor (CB1R) is only stably surface expressed in axons, where it downregulates neurotransmitter release. How this tightly regulated axonal surface polarity is established and maintained is unclear. To address this question, we used time-resolved imaging to determine the traff...
Autores principales: | Fletcher-Jones, Alexandra, Hildick, Keri L, Evans, Ashley J, Nakamura, Yasuko, Wilkinson, Kevin A, Henley, Jeremy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491034/ https://www.ncbi.nlm.nih.gov/pubmed/31036155 http://dx.doi.org/10.7554/eLife.44252 |
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