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Dual separable feedback systems govern firing rate homeostasis

Firing rate homeostasis (FRH) stabilizes neural activity. A pervasive and intuitive theory argues that a single variable, calcium, is detected and stabilized through regulatory feedback. A prediction is that ion channel gene mutations with equivalent effects on neuronal excitability should invoke th...

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Detalles Bibliográficos
Autores principales: Kulik, Yelena, Jones, Ryan, Moughamian, Armen J, Whippen, Jenna, Davis, Graeme W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491091/
https://www.ncbi.nlm.nih.gov/pubmed/30973325
http://dx.doi.org/10.7554/eLife.45717