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Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma
BACKGROUND: Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood. In this study, we identified the role of exosomal microRNAs (miRNAs) from TMZ-resistant cells as important mediators of chemoresistan...
Autores principales: | Yin, Jianxing, Zeng, Ailiang, Zhang, Zhuoran, Shi, Zhumei, Yan, Wei, You, Yongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491393/ https://www.ncbi.nlm.nih.gov/pubmed/30917935 http://dx.doi.org/10.1016/j.ebiom.2019.03.016 |
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