Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy

Leber hereditary optic neuropathy (LHON) is a syndrome of subacute loss of central vision associated with mutations in mitochondrial DNA coding for components of complex I. LHON preferentially involves small axons in the temporal optic nerve, but the reason is unclear. We performed a Monte Carlo sim...

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Detalles Bibliográficos
Autores principales: Coussa, Razek Georges, Merat, Pooya, Levin, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491426/
https://www.ncbi.nlm.nih.gov/pubmed/31040363
http://dx.doi.org/10.1038/s41598-019-43180-z

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