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A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair
Uropathogenic E. coli experience a wide range of osmolarity conditions before and after successful infection. Stress-responsive regulatory proteins in bacteria, particularly proteins of the Hha family and H-NS, a transcription repressor, sense such osmolarity changes and regulate transcription throu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491433/ https://www.ncbi.nlm.nih.gov/pubmed/31040281 http://dx.doi.org/10.1038/s41467-019-10002-9 |