Targeting GPER1 to suppress autophagy as a male-specific therapeutic strategy for iron-induced striatal injury

The functional outcome of intracerebral hemorrhage (ICH) in young male patients are poor than in premenopausal women. After ICH, ferrous iron accumulation causes a higher level of oxidative injury associated with autophagic cell death in striatum of male mice than in females. In rodent model of ferr...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Yun, Lin, Chih-Lung, Wang, Li-Fang, Tsai, Ke-Li, Lin, Jun-Yu, Hsu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491488/
https://www.ncbi.nlm.nih.gov/pubmed/31040364
http://dx.doi.org/10.1038/s41598-019-43244-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491488/
https://www.ncbi.nlm.nih.gov/pubmed/31040364
http://dx.doi.org/10.1038/s41598-019-43244-0

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